Research Article

Overexpression of S6 Kinase 1 in Brain Tumours Is Associated with Induction of Hypoxia-Responsive Genes and Predicts Patients' Survival

Figure 2

S6K1 gene overexpression in brain tumours compared to normal brain is associated with patients’ poor survival. Data sets in a single panel were from the same study. Gene expression profile [GEP] data are log transformed and normalized as previously described [26]. In brackets, are indicated the number of samples. (a) Comparison of S6K1 gene expression profile in brain tumours French Brain Study [27] compared to normal brain. (b) Comparison of S6K1 gene expression profile in brain tumours in both alive and dead subjects at 3 and 5 years of survival.
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(a)
416927.fig.002b
(b)