Early Response to Dexamethasone as Prognostic Factor: Result from Indonesian Childhood WK-ALL Protocol in Yogyakarta

Table 1

Characteristics of patients.

	Poor responder (𝑁=32)		Good responder (𝑁=133)		Total (𝑁=165)		P value
	𝑛	(%)	𝑛	(%)	𝑛	(%)
Risk group
Standard risk	10^a	31.3	90	67.7	100	60.6	<0.01
High risk	22	68.8	43	32.3	65	39.4
Gender
Girl	14	43.8	54	40.6	68	41.2	0.75
Boy	18	56.3	79	59.4	97	58.8
Age group (NCI criteria)^b
Standard risk	21	65.6	118	88.7	139	84.2	<0.01
High risk	11	34.4	15	11.3	26	15.8
WBC count (/μL)
<50,000	14	43.8	111	83.5	125	75.8	<0.01
≥50,000	18	56.2	22	16.5	40	24.2
Median (range)	70,000  (2,000–424,000)		7,800  (600–346,000)
Peripheral lymphoblasts count at diagnosis (%)^c
0–49	7	21.9	65	49.6	72	44.2	<0.01
50–100	25	78.1	66	50.4	91	55.8

^aOf 10 standard risk patients with poor response, 7 moved to high risk and 3 were still in standard risk by mistake. ^bStandard risk (1–9 years), high risk (10–14 years and infant <1 year (including 1 patient)). ^cData not available in 2 patients.