Early Response to Dexamethasone as Prognostic Factor: Result from Indonesian Childhood WK-ALL Protocol in Yogyakarta

Table 4

Univariate and multivariate analyses of factors predicting event-free survival.

Factors	HR	95% CI	𝑃 value
Univariate analyses
Age at diagnosis	2.05^1	1.31–3.22	0.02
WBC group at diagnosis	1.98^2	1.34–2.92	0.01
Early response to treatment	1.91^3	1.25–2.91	0.03
Gender	1.03^4	0.72–1.46	0.87
Multivariate analysis ^a
Age at diagnosis	1.75	1.10–2.79	0.018
WBC group at diagnosis	1.77	1.18–2.66	0.006

^aFinal model. Age at diagnosis, WBC group, and early response were included as factors in a stepwise analysis. All three were also used for stratification into HR group. The model was found using forward selection.
¹For age <1 and ≥10 years relative to 1–9 years.
²For WBC ≥ 50,000 relative to WBC < 50,000.
³For poor responders relative to good responders.
⁴For girls relative to boys.