Journal of Oncology / 2012 / Article / Tab 3

Clinical Study

Selenium in the Prevention of Anthracycline-Induced Cardiac Toxicity in Children with Cancer

Table 3

Se-supplemented patients with low serum Se levels, high Pro-BNP levels, and/or cardiac failure.

Pt.
Total anthracy
mg/m2
Pro-BNP
pg/mL
Se
mcg/L
ECHO Cardiac failure Digoxin
Enalapril
Furosem
Se
Suppl.
End results
Echo(i) Pro-BNP 
(pg/mL)
(ii) Pro-BNP
(pg/mL)
(i) Se
(mcg/L)
(ii) Se
(mcg/L)

ES55075470Systolic failure++100 mcgNormal536123.510886
NBL18017552Systolic failure++100 mcgNormal8595103106
ACC4001071Diastolic failure100 mcgNormal10106575
HL30084355Diastolic failure100 mcgNormal2981187281
NHL24017249.2Normal100 mcgNormal12.6NA109NA
HL400197.5 20Normal100 mcgNormal80NA208NA
BL150170.457Normal100 mcgNormal2NA75NA
NHL12027783Systolic failure++100 mcgNormalNANANANA
RMS012762Intracardiac thrombusNormal67NANANA
AML400802265NormalDied NANANANA
TALL3201536129Pericardial effusion, tamponade Died NANANANA

Pt: patient; NA: not available, ES: Ewing’s sarcoma, NBL: neuroblastoma, ACC: adrenocortical carcinoma, HL: Hodgkin lymphoma, NHL: non-Hodgkin lymphoma, BL: Burkitt lymphoma, RMS: rhabdomyosarcoma, AML: acute myeloid leukemia; T ALL: T acute lymphoblastic leukemia.

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