Selenium in the Prevention of Anthracycline-Induced Cardiac Toxicity in Children with Cancer

Table 4

Pre- and postsupplementation levels in Se-supplemented patients with low serum Se levels and high Pro-BNP levels and/or cardiac failure.

𝑛=8	Presupplementation levels,; range (median)	1st postsupplementation levels, range (median)	2nd postsupplementation levels, range (median)
Pro-BNP (pg/mL)	10–843 (175)	2–536 (73.5)*	10–123.5 (106.5)**
Se (mcg/L)	20–83 (57)	65–109 (103)***	75–106 (83)****

* 𝑃=0.018.
** 𝑃=0.109.
*** 𝑃=0.028.
**** 𝑃=0.068.
Wilcoxon sign test was used; median and range were given as descriptive statistics.