Full-Length Enrich c-DNA Libraries-Clear Cell-Renal Cell Carcinoma

Table 3

Expression levels of MYC-target genes in ccRCC and adjacent normal tissues.

Gene name	Normal kidney versus ccRCC^† (𝑃 value^‡)	Correlation coefficient with MYC expression level of ccRCC tissues (𝑃 value)^§
BCL2	−6.58±0.12versus−3.84±0.17(<0.001)	0.45 (0.002)*
CCND1	−4.45±0.14versus−2.62±0.18(<0.001)	0.31 (0.038)*
PCNA	−5.78±0.14versus−4.76±0.13(<0.001)	0.33 (0.038)*
PGK1	−3.40±0.18versus−2.70±0.14(<0.001)	0.42 (0.004)*
VEGFA	−3.93±0.30versus−1.23±0.21(<0.001)	0.36 (0.016)*

^†Expression levels of MYC-target genes (−ΔCt_GENE-TPT1values) measured by Q-PCR in 44 tissues were represented as mean ± SE.
^‡Significance of difference was determined by paired-samples Student’s 𝑡 test.
^§Correlation between the expression levels of MYC and MYC-target genes in ccRCC tissues was determined by Pearson correlation method.
* 𝑃<0.05 was considered statistically significant.