Clinical Study
Plasma Vascular Endothelial Growth Factor Dysregulation in Defining Aggressiveness of Head and Neck Squamous Cell Carcinoma
Table 5
VEGF/sVEGFR-1 and VEGF secretion patterns in normal controls and patients with low-grade and high-grade tumors.
| | VEGF | sVEGFR-1 | Normal controls, (%) | Low-grade tumor, | High-grade tumor, (%) | | pg/mL | pg/mL | () | (%) () | () |
| | Very high, VHH > 84.5 | High, RH ≥ 34.5 | 0 (0) | 3 (6) | 7 (21.9) | | Low, RL < 34.5 | 5 (15.6) | 3 (6) | 5 (15.6) |
| | Total | 5 (15.6) | 6 (12) | 12 (37.5) |
| | High, VH 32.5–84.5 | High, RH ≥ 34.5 | 1 (3.1) | 4 (8) | 9 (28.1) | | Low, RL < 34.5 | 4 (12.5) | 3 (6) | 2 (6.3) |
| | Total | 5 (15.6) | 7 (14) | 11 (34.4) |
| | Intermediate, VI 23.2–32.5 | High, RH ≥ 34.5 | 1 (3.1) | 7 (14) | 4 (12.5) | | Low, RL < 34.5 | 4 (12.5) | 6 (12) | 0 (0) |
| | Total | 5 (15.6) | 13 (26) | 4 (12.5) |
| | Low, VL < 23.2 | High, RH ≥ 34.5 | 5 (15.6) | 13 (26) | 3 (9.4) | | Low, RL < 34.5 | 12 (37.5) | 11 (22) | 2 (6.3) |
| | Total | 17 (53.1) | 24 (48) | 5 (15.6) |
|
|
