Early Detection Biomarkers for Ovarian Cancer

Table 3

Levels of expression of biomarker ALDH1 in various stages of ovarian cancer.

Biomarker	Expression pattern on tumors	Category	N	Positive rates; (levels of expression)	References
	Low to high	Serous stages III-IV	65	0% in 27.1% of samples	[124]
				1%–20% in 44% of samples
				20%–100% in 28.9% of samples; (10% of all patients demonstrated nearly 100% expression)
	Low	Malignant tumors	5	17.1%  ± 7.61%	[125]
ALDH1		Benign tumors	5	31.03%  ± 6.68%
		Healthy controls	5	37.4%  ± 5.4%
	Low to high	Serous carcinoma	266	>20% expression in 85% of samples	[121]
		Stage I	32	>20% expression in 44% of samples
	Low and high	Late stage	65	77% positive cells	[126]