Synergistic Effect of Garcinol and Curcumin on Antiproliferative and Apoptotic Activity in Pancreatic Cancer Cells
Garcinol and curcumin significantly increased Caspase-3 (a and b) and Caspase-9 (c and d) activity by ~2 to 3 folds in both PaCa cell lines: BxPC-3 (left panel) and Panc-1 (right panel) relative to untreated control after 48 hour treatment. Caspase activity was measured in garcinol- and/or curcumin-treated whole cell extracts using colorimetric assay. * relative to control.
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