Clinical Significance of Langerhans Cells in Squamous Cell Carcinoma of the Larynx

Table 1

Relationship between LCs and subpopulations in tumor-infiltrating leukocytes in squamous cell carcinoma of the larynx.

Tumors with ≤7 LC/HPF versus tumors with >7 LC/HPF*
Means values in each group of tumors
Parameter**	≤7 LC/HPF	>7 LC/HPF	Significance
Leucocytes (CD45)	60.5	92.4
Macrophages (MO1)	19.07	14.48
B cells (IOM-1)	1.69	3.85
T cells (CD3)	31.2	51.6
Cytotoxic/suppressor T cells (CD8)	14.4	25.7
T cell/macrophage ratio (CD3/CD11b)	1.97	3.79
CD4/CD8	2	1.2

*Average counting 10 high-power fields. **Mean values for number of TIL or ratios.