Journal of Oncology / 2012 / Article / Fig 2

Review Article

Targeting Angiogenesis for Controlling Neuroblastoma

Figure 2

Schematic presentation of molecular changes associated with N-Myc amplification in neuroblastoma. Amplified N-Myc after heterodimerization with Max augments synthesis of several genes and through PI3K/Akt-mediated pathway regulates VEGF signaling resulting in neuroblastoma tumorigenesis.
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