Journal of Oncology / 2012 / Article / Fig 2

Review Article

Targeting Angiogenesis for Controlling Neuroblastoma

Figure 2

Schematic presentation of molecular changes associated with N-Myc amplification in neuroblastoma. Amplified N-Myc after heterodimerization with Max augments synthesis of several genes and through PI3K/Akt-mediated pathway regulates VEGF signaling resulting in neuroblastoma tumorigenesis.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.