Clinical Study

An Observational Study of the First Experience with Bevacizumab for the Treatment of Patients with Recurrent High-Grade Glioma in Two Belgian University Hospitals

Table 2

BEV related adverse events.

DescriptionGrade 1Grade 2Grade 3TotalTreatment regimen

Likely related to BEV therapy
 Hypertension110210 mg/kg/2weeks
 Epistaxis010110 mg/kg/2weeks
 Ulceration skin101210 mg/kg/2weeks
 Hematochezia10011 cycle at 5 mg/kg/2weeks;
9 cycles at 10 mg/kg/2weeks
 Subungual hemorrhage100110 mg/kg/2weeks
 Wound dehiscence01*0110 mg/kg/2weeks
 Abdominal pain syndrome001110 mg/kg/2weeks
Total4329

*Occurred more than 2 months after termination of BEV therapy.