An Observational Study of the First Experience with Bevacizumab
for the Treatment of Patients with Recurrent High-Grade Glioma in
Two Belgian University Hospitals
Table 2
BEV related adverse events.
Description
Grade 1
Grade 2
Grade 3
Total
Treatment regimen
Likely related to BEV therapy
Hypertension
1
1
0
2
10 mg/kg/2weeks
Epistaxis
0
1
0
1
10 mg/kg/2weeks
Ulceration skin
1
0
1
2
10 mg/kg/2weeks
Hematochezia
1
0
0
1
1 cycle at 5 mg/kg/2weeks;
9 cycles at 10 mg/kg/2weeks
Subungual hemorrhage
1
0
0
1
10 mg/kg/2weeks
Wound dehiscence
0
1*
0
1
10 mg/kg/2weeks
Abdominal pain syndrome
0
0
1
1
10 mg/kg/2weeks
Total
4
3
2
9
*Occurred more than 2 months after termination of BEV therapy.