Table 5: Endothelial cell proliferation (ECP)/tumour cell proliferation (TCP).

Growth patternNumber of CRLMECP mean: 95% CI intervalTCP mean: 95% CI intervalECP/TCP mean: 95% CI interval

Desmoplastic160.020: 95% 0.013–0.0400.50: 95% 0.28–0.890.048: 95% 0.029–0.079
Pushing210.028: 95% 0.020–0.0400.16: 95% 0.10–0.260.160: 95% 0.093–0.270
Replacement130.019: 95% 0.011–0.0300.27: 95% 0.20–0.380.068: 95% 0.039–0.120
Mixed120.020: 95% 0.012–0.0360.16: 95% 0.11–0.290.113: 95% 0.066–0.196

ECP: endothelial cell proliferation, TCP: tumour cell proliferation and ECP/TCP which is the value representing angiogenesis dependent growth.
ECP/TCP, pushing versus desmoplastic, 𝑃 = 0 . 0 0 0 7 .
ECP/TCP, pushing versus replacement, 𝑃 = 0 . 0 2 1 .