Altered and RB1 Expressions Are Associated with Poor Prognosis in Patients with Nonsmall Cell Lung Cancer
Figure 3
RB1 immunohistochemical staining in lung cancer samples. The represesntative patterns of expression range from strong (3+) in a mixed adenocarcinoma (a), a large cell neuroendocrine carcinoma (b), moderate (2+) in a large cell neuroendocrine carcinoma (c), and weak (1+) in an adenocarcinoma with acinar differentiation, respectively, in the nuclei of tumor cells. No (0) expression was seen in tumor cells of an mixed adenocarcinoma (e). However, weak expression (1+) is present in normal lung tissue (f) or stroma.
