Altered 𝐩𝟏𝟔^{𝐈𝐍𝐊𝟒} and RB1 Expressions Are Associated with Poor Prognosis in Patients with Nonsmall Cell Lung Cancer

Table 1

Comparison of p16, histology, FISH, and five-year survival rate¹.

p16 IHC	Overall*		Adenocarcinoma**		Nonadenocarcinoma***		CNV CDKN2A***
	Alive	Dead	Alive	Dead	Alive	Dead	Gain; (ratio > 2)	Loss; (ratio = 0)	Loss; (ratio = 0.5)	Normal; (ratio = 1)
Positive	4 (12.5)	18 (43.9)	5 (18.5)	12 (50.0)	0 (0.0)	5 (29.4)	7 (77.8)	0 (0.0)	3 (33.3)	12 (10.0)
Negative	28 (87.5)	23 (56.1)	22 (81.5)	12 (50.0)	5 (100.0)	12 (70.6)	2 (22.2)	5 (100)	6 (66.7)	35 (90.0)

¹The data presented in the table in format of “case number (% of the same column)”.
Fisher’s probability exact test (two tailed): *𝑃=0.004, **𝑃=0.036, ^***not done.