Early Pseudoprogression following Chemoradiotherapy in Glioblastoma Patients: The Value of RANO Evaluation

Figure 1

T1-contrast-enhanced and FLAIR magnetic resonance imaging (MRI) documenting pseudoprogression. Compared with pre-RT/TMZ MRI, the 1-month post-RT/TMZ showed increasing areas of contrast enhancement suggestive of tumoral progression. The patient remained clinically stable with stable dose of corticotherapy. Adjuvant TMZ treatment cycles were maintained and serial MRI at 4, 7, 10, and 15 months showed a consistent reduction in the size and the contrast of the lesion as well as in FLAIR signal.