Proteomics of Uveal Melanoma: A Minireview

Table 3

Differences in protein levels between primary UM with and without subsequent metastasis.

No.	Gene name	Protein name	Average ratio	𝑡-test
1	PDIA3	Protein disulfide-isomerase A3 precursor	1,5	0,011
2	VIM	Vimentin	1,8	0,007
3	SELENBP1	Selenium-binding protein 1	1,3	0,044
4	ENO1	Alpha-enolase	1,4	0,007
5	EIF2S1	Eukaryotic translation initiation factor 2 subunit 1	−1,6	0,035
6	CAPZA1	F-actin capping protein subunit alpha-1	1,3	0,028
7	PSMA3	Proteasome subunit alpha type 3	−1,2	0,026
8	RPSA	40S ribosomal protein SA	−1,4	0,023
9	ERP29	Endoplasmic reticulum protein ERp29	1,4	0,040
10	TPI1	Triosephosphate isomerase	1,7	0,00009
11	PARK7	Protein DJ-1	1,2	0,018
12	TUBB	Tubulin beta chain	−1,7	0,017
13	TUBA1B	Tubulin alpha-1B chain	−1,9	0,006
14	FABP3	Fatty acid-binding protein, heart	2,2	0,00035

A selection of proteins differentially expressed between primary UM with and without metastasis. Adopted from Linge et al. [38]. Ratios were calculated as the difference between primary UM that subsequently metastasized versus primary UM that did not metastasize.