Antiproliferative and Apoptotic Effects of a Specific Antiprostate Stem Cell Single Chain Antibody on Human Prostate Cancer Cells
Figure 5
Dot plot analysis of Annexin-V/PI assay using PSCA-expressing DU145 cells. The lower left quadrant contains vital population and the lower right contains the apoptotic (AnnexinV+/PI−) population. Untreated cells (control) (a), scFv C5-I treated cells (b), and scFv C5-II treated cells (c). The scFv C5-II induced apoptosis 33.8% in DU-145 cells while the apoptotic indexes 1.48% and 2.74% were detected for scFv C5-I treated cells and untreated cells, respectively.
