Absence of HPV Infection Is Associated with Smoker Patients with Squamous Cell Carcinoma of the Oropharynx

Table 1

Comparisons between the clinical characteristics of the HPV-positive and HPV-negative cancers of the oropharynx, using the Exact Fisher or chi-square test.

Variables	Patients	HPV+	HPV−
Age				0.4870
31–44 years	11	4	7
≥45 years	26	8	18
Sex				0.0908
Male	33	9	24
Female	4	3	1
Alcohol				0.5937
Alcoholic	30	10	20
Abstainer	7	2	5
Tobacco				0.0283*
Nonsmoker	3	3	0
Level-1 smoker^b	14	3	11
Level-2 smoker^b	20	6	14
Stages				0.6092
I or II	12	3	9
III or IV	25	9	16

Exact Fisher or chi-square test. ^bCumulative consumption: level-1 smoker? 28 pack-years; level-2 smoker >28 pack-years. *Statistically significant value.