AR-A 014418 Used against GSK3beta Downregulates Expression of hnRNPA1 and SF2/ASF Splicing Factors
Figure 3
(a) qRTPCR analysis of BCL2, BCL-xL, Survivin, MCL1, and BMI1 in glioma cell lines treated or untreated with AR-A 014418 (50 μM) for 24 hrs. Means S.E.; ; . (b) Soft agar assay to estimate the tumorigenic propensity of U87 cells in presence of AR-A 014418 (50 μM) and LY294002 (10 μM), observed for 10 days and 20 days.