Journal of Oncology

Review Article

Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF-β-, Notch-, and Wnt-Mediated EMT

Table 3

List of experimentally validated miRNA—gene interactions for Notch signalling pathway. Interactions with Wnt and TGF- signalling are also indicated (genes among those in Notch pathway).
miRNAGene (Notch pathway)Wnt signallingTGF- signalling
hsa-miR-335-5pNUMB, MFNG, LFNG, DLL1, NOTCH3, DTX1, MAML2, JAG2——
hsa-miR-34a-5pHDAC1, NOTCH2, NOTCH1, DLL1, JAG1——
hsa-miR-1CTBP1, CTBP2, NOTCH2, HDAC2, DTX1CTBP1, CTBP2—
hsa-miR-124-3pRBPJ, DVL2, MAML1, JAG2DVL2—
hsa-miR-26b-5pDVL3, KAT2B, EP300EP300, DVL3EP300
hsa-miR-155-5pNOTCH2, PSEN1, RBPJ——
hsa-miR-375NUMB, JAG1, RBPJ——
hsa-miR-21-5pJAG1, NCSTN, DTX3L——
hsa-miR-98DTX4, JAG1——
hsa-miR-122-5pNUMBL, ADAM17——
hsa-miR-200c-3pJAG1, EP300EP300EP300
hsa-miR-9-5pNCOR2, EP300EP300EP300
hsa-miR-324-3pCREBBP, DVL2CREBBP, DVL2CREBBP
hsa-miR-24-3pHDAC1, NOTCH1——
hsa-miR-194-5pEP300EP300EP300
hsa-miR-92a-3pKAT2B——
hsa-miR-16-5pNOTCH2——
hsa-miR-93-5pKAT2B——
hsa-miR-19a-3pKAT2B——
hsa-miR-103a-3pNUMB——
hsa-miR-132-3pLFNG——
hsa-miR-30a-5pNOTCH1——
hsa-miR-200b-3pEP300EP300EP300
hsa-miR-19b-3pKAT2B——
hsa-miR-145-5pAPH1A——
hsa-miR-31-5pNUMB——
hsa-miR-429EP300EP300EP300
hsa-miR-10a-5pNCOR2——
hsa-miR-182-5pEP300EP300EP300
Hsa-miR-374a-5pEP300EP300EP300