Review Article

Orthotopic Heart Transplantation and Mechanical Circulatory Support in Cancer Survivors: Challenges and Outcomes

Table 1

Factors that may influence outcome after advanced heart failure therapies in adult patients with anthracycline-induced cardiomyopathy [1].

Patient characteristics that may favor advanced heart failure therapies in anthracycline-induced end-stage heart failurePatient characteristics that may oppose advanced heart failure therapies in anthracycline-induced end-stage heart failure

Lower body surface areaHigher rates of malignancy*
Lower likelihood of diabetesHigher rates of infection
Lower likelihood of hypertensionImpact of prior thoracic radiation therapy on sternotomy complications
Lower likelihood of smokingGreater need for right ventricular assist device
Higher rates of perioperative bleeding
Younger ageHigher rates of destination-therapy (as opposed to bridge to transplantation)#

ā€‰*Applies to orthotopic heart transplantation but not left ventricular assist device.
#Applies to left ventricular assist device but not to orthotopic heart transplantation.