Research Article

Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection

Table 2

Treatment characteristics.

Characteristics (%)

Stereotactic radiosurgery
 Median tumor volume (cm3)0.688
 Range tumor volume (cm3)0.056–33.57
 Median number of beams202
 Median number of monitor units14741.26
 Median dose per fraction (Gy)22
 Range dose per fraction (Gy)5–22
 Median total dose (Gy)22
 Range total dose (Gy)12–30
 Median number of fractions1
 Range number of fractions1–5
 Median coverage (%)96.39
 Median isodose line (%)76
 Range isodose line (%)58–89
 Median conformality index1.3
 Median homogeneity index1.32
 Median minimum dose (Gy)2037.18
 Median maximum dose (Gy)2822.02
Surgical resection
(patients)24
 Gross total resection22 (91.7)
 Subtotal resection2 (8.3)
Whole-brain radiation therapy (WBRT)
total12 (18.2)
WBRT prior to SRS6 (9.1)
WBRT after SRS6 (9.1)
 Median total dose (Gy)30
 Dose range (Gy)20–37.5
 Median dose for WBRT prior to SRS (Gy)30
 Dose range for WBRT prior to SRS (Gy)20–30
Systemic therapy
(patients)56 (84.8)
 Standard25 (44.6)
 Experimental5 (9)
 Both26 (46.4)