Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection

Table 3

Prognostic factors.

Variable	Statistical analysis
	Log-rank	Multivariate Cox regression
	value	value	Coefficient (Coeff.)	95% Confidence interval (CI)
Survival
Age	0.0000	0.038	0.0338118	0.0018982–0.0657254
Prior surgery	0.0486	0.053	0.6203678	−1.24931–0.0085739
Prior WBRT	0.0097	0.014	1.104396	0.2219025–1.986891
RPA	0.0000	0.000	2.153972	1.108619–3.199326
KPS (≥70 versus <70)	0.0000	0.000	2.072708	0.9231157–3.222301
SIR (≥6 versus <6)	0.0093	0.011	2.155395	0.1726184–1.36333
BSBM	0.0027	0.003	−0.8503598	−1.402409–−0.2983109
Number of brain metastases (>3 versus ≤3)	0.0009	0.002	1.260513	0.462241–2.058785
Ds-GPA	0.0002	0.000	0.5929137	−0.7985645–−0.2468485
Initial tumor volume	0.0000	0.651	0.008675	−0.0289586–0.0463086
Local control
Tumor volume	0.0000	0.668	−0.0242895	−0.1353437–0.0867646
Distant brain progression-free survival
Prior WBRT	0.0072	0.014	1.252507	0.2539636–2.25105