Review Article

Gallbladder Cancer in the 21st Century

Table 6

Efficacy of gemcitabine combination therapy in patients with advanced gallbladder and biliary tract cancer.

RegimensNumber of patientsResponse rate (%)Median overall survival (months)

Gemcitabine and cisplatin
 Meyerhardt et al. [128]33219.7
 Thongprasert et al. [129]40268.4
 Lee et al. [130]24219.3
 Kim et al. [131]293511
Gemcitabine and oxaliplatin
 Harder et al. [132]312611
 André et al. [133]33; 2336; 2215.4; 7.6
 Gebbia et al. [134]245014
Gemcitabine an capecitabine
 Knox et al. [118]453114
 Cho et al. [117]443214
 Riechelmann et al. [135]752912.7
 Iyer et al. [136]121714

Patients with good performance status; patients with poor performance status. Modified from [2].