Correlation of Beta-2 Adrenergic Receptor Expression in Tumor-Free Surgical Margin and at the Invasive Front of Oral Squamous Cell Carcinoma
Table 2
Association between histopathological parameters and β2-AR expression in 62 patients with oral squamous cell carcinoma.
Beta-2 adrenergic receptor
Variable
Tumor-free margin
Invasive tumor front
Weak ()
Moderate/strong ()
Weak/negative ()
Moderate/strong ()
(%)
(%)
(%)
(%)
Malignancy grading
M. diff.
10 (83.3)
44 (88)
0.645
31 (86.1)
23 (88.5)
0.999
L. diff.
2 (16.7)
6 (12)
5 (13.9)
3 (11.5)
Vascular embolization
Yes
9 (75)
26 (52)
0.149
23 (63.9)
12 (46.2)
0.165
No
3 (25)
24 (48)
13 (36.1)
14 (53.8)
Perineural infiltration
Yes
9 (75)
36 (72)
0.999
24 (66.7)
21 (80.8)
0.219
No
3 (25)
14 (28)
12 (33.3)
5 (19.2)
Muscular infiltration
Yes
11 (91.7)
43 (86)
0.999
31 (86.1)
23 (88.5)
0.999
No
1 (8.3)
7 (14)
5 (13.9)
3 (11.5)
Bone infiltration
Yes
1 (8.3)
5 (10.2)
0.999
5 (14.3)
1 (3.8)
0.227
No
11 (91.7)
44 (89.8)
30 (85.7)
25 (96.2)
Lymph node involvement
N+
4 (33.3)
26 (52)
0.245
18 (50)
12 (46.2)
0.765
N0
8 (66.7)
24 (48)
18 (50)
14 (53.8)
: number of cases; : value obtained by chi-square test or Fisher’s exact test; M. diff.: more differentiated tumor; L. diff.: less differentiated tumor; excluding patients with lost records.
