Journal of Oncology / 2016 / Article / Tab 2

Clinical Study

Does the Degree of Hepatocellular Carcinoma Tumor Necrosis following Transarterial Chemoembolization Impact Patient Survival?

Table 2

Multivariable analyses of post-TACE survival.

UnivariateMultivariable
Hazard ratio95% CI valueHazard ratio95% CI value

Age0.99(0.98, 1.01)0.5001.00(0.98, 1.02)0.721

Gender0.2950.167
 Male1.00 (reference)(—, —)1.00 (reference)(—, —)
 Female1.23(0.84, 1.79)0.2951.35(0.88, 2.06)0.167

Race0.1080.132
 White1.00 (reference)(—, —)1.00 (reference)(—, —)
 Black0.88(0.58, 1.36)0.75(0.47, 1.19)0.222
 Other1.91(0.99, 3.68)1.57(0.80, 3.08)0.194

Child-Pugh<0.0001<0.0001
 A1.00 (reference)(—, —)1.00 (reference)(—, —)
 B2.17(1.50, 3.15)<0.0012.67(1.80, 3.94)<0.001
 C2.09(1.05, 4.16)0.0372.26(1.09, 4.65)0.028

Total tumor diameter1.04(1.01, 1.07)0.0091.04(1.01, 1.08)0.009

mRECIST0.0340.003
 Complete1.00 (reference)(—, —)1.00 (reference)(—, —)
 Partial1.15(0.77, 1.72)0.4991.18(0.85, 2.14)0.436
 Stable1.39(0.83, 2.33)0.2091.28(0.55, 2.03)0.379
 Progressive3.21(1.42, 7.24)0.0054.99(1.19, 11.09)<0.0001

Sum axial diameter of three largest hepatocellular carcinoma tumors.
Multiple degree of freedom test to determine if any of the levels within the categorical variables differs from the reference group within that variable.
TACE: transarterial chemoembolization; mRECIST: modified Response Evaluation Criteria In Solid Tumors, value: probability, and 95% CI: 95% confidence interval.