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Journal of Oncology
Volume 2016 (2016), Article ID 5473681, 7 pages
http://dx.doi.org/10.1155/2016/5473681
Research Article

Precancerous Cervix in Human Immunodeficiency Virus Infected Women Thirty Years Old and above in Northern Uganda

1Institute of Public Health and Management, International Health Sciences University, P.O. Box 7782, Kampala, Uganda
2Uganda Society for Health Scientists, Department of Anatomy, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda
3The AIDS Support Organization, TASO Gulu, P.O. Box 347, Gulu, Uganda
4Department of Gynecology and Obstetrics, College of Health Sciences, Makerere University, P.O. Box 7072, Kampala, Uganda

Received 25 January 2016; Revised 6 June 2016; Accepted 14 June 2016

Academic Editor: Peter E. Schwartz

Copyright © 2016 Jonathan Izudi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Little is known about precancerous cervical lesion (PCCL), the precursor of cervical cancer among Human Immunodeficiency (HIV) infected women in a postconflict setting of Northern Uganda. Objective. To establish factors associated with PCCL among HIV infected women above thirty years of age in a postconflict setting of Northern Uganda. Method. This retrospective cohort study used electronic data from 995 HIV-positive women that attended cervical cancer screening during June 2014 and December 2015. Data on social, sexual, obstetric, and gynecological factors was analyzed at 95% confidence level. Multivariate analysis determined factors independently associated with positive PCCL. Probability value less than 5% was considered significant. Results. Prevalence of PCCL was 3.0% (95% confidence interval (CI): 2.0–4.3). A positive PCCL was significantly associated with absence of sexually transmitted diseases (STDs) during clinic visits (adjusted odds ratio, aOR = 0.24; 95% confidence interval (CI): 0.09–0.64; ) and first pregnancy before the age of 20 years (aOR = 3.09; 95% CI: 1.21–7.89; ). Conclusion. The prevalence of PCCL was low in the postconflict setting of Northern Uganda. HIV-positive women presenting with STDs and those with first pregnancy before the age of 20 years were at increased risk of PCCL.