Research Article

Frequency of BCR-ABL Transcript Types in Syrian CML Patients

Table 2

Frequency of BCR-ABL transcript types among CML patient groups ().

Patient groupBCR-ABL transcript types
b2a2 b3a2b3a3e1a3

Imatinib-treated patients ()
BCR-ABL ≤ 0.1% ()6 of 10 (60%)1 of 10 (10%)1 of 10 (10%)2 of 10 (20%)
BCR-ABL > 0.1% ()3 of 8 (37.5%)4 of 8 (50%)1 of 8 (12.5%)0 of 8 (0%)

Noncompliant patients ()5 of 60 of 61 of 60 of 6

Dual transcripts were detected in three patients, which explains reporting 24 transcripts in 21 patients.
Independence of BCR-ABL transcript types among imatinib-treated patients according to their molecular response was analyzed by Fisher’s exact test. value < 0.05 was considered significant.