Ki-67 Expression by Immunohistochemistry and Quantitative Real-Time Polymerase Chain Reaction as Predictor of Clinical Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

Table 1

Patient characteristics.

Characteristics	Number (%)	value
Age
≤50	27 (56.3)	0.076
>50	21 (43.8)
Grade
Low grade	8 (16.7)	0.057
Moderate	26 (54.2)
High grade	14 (29.2)
Subtype
Luminal A	10 (20.8)	0.131
Luminal B	20 (41.7)
Her2	14 (29.2)
Triple negative	4 (8.3)
Ki-67 (SD)
Positive	26 (54.2)	0.025
Negative	22 (45.8)
Mean of tumor size (SD)
Before chemotherapy	12.60 (0.40)	0.031
After chemotherapy	08.06 (0.20)

Chi Square statistical test; Wilcoxon’s statistical test; SD = standard deviation.