Multifactorial Analysis of Mortality in Screening Detected Lung Cancer

Table 3

Cox proportion hazard model suggested that emphysema and moderate to severe CAC were stronger predictors of nonsurvival in patients with lung cancer detected in the NLST compared to skeletal muscle area and fat attenuation. Numbers in parenthesis represent 95% confidence interval.

Variables	Hazard ratio (HR)	Coefficient	value
Muscle area	0.96 (0.93–0.98)	−0.04	0.008
Fat attenuation	1.11 (1.06–1.16)	0.10	<0.001
Emphysema	7.55 (1.49–38.29)	2.02	0.015
Minimal CAC	1.20 (0.62–2.33)	0.18	0.588
Moderate CAC	2.91 (1.56–5.43)	1.07	0.001
Severe CAC	2.39 (1.26–4.53)	0.87	0.007