Prognostic Factors Predicting Poor Outcome in Cancer Patients with Febrile Neutropenia in the Emergency Department: Usefulness of qSOFA

Table 1

Comparison of clinical characteristics of 104 cancer patients presented with febrile neutropenia to the emergency department including 25 case patients who admitted to the intensive care unit or died in the hospital and 79 control patients who admitted to general wards and discharged.

Characteristics	Total (n = 104)	Case (n = 25)	Control (n = 79)	P value
Age	60.8 ± 13.6	63.6 ± 12.9	61 (51-69)	0.255
Male, no. (%)	41 (39)	14 (56)	27 (34)	0.052
Comorbid conditions, no. (%)
Diabetes mellitus	14 (13)	5 (20)	9 (11)	0.316
Cardiovascular disease	6 (6)	1 (4)	5 (6)	1.0
Respiratory disease	5 (8)	1 (4)	4 (5)	1.0
Chronic renal failure	8 (8)	3 (12)	5 (6)	0.394
Liver cirrhosis	3 (3)	1 (4)	2 (3)	0.565
Rheumatologic disease	1 (1)	1 (4)	0	0.240
Neurodegenerative disease	6 (6)	2 (8)	4 (5)	0.628
Clinical manifestation
ED visits on weekends	36 (35)	9 (36)	27 (34)	0.868
Mental change	6 (6)	3 (12)	3 (4)	0.148
Fever > 24 hr	33 (32)	4 (16)	27 (34)	0.343
Presence of central venous catheter	17 (16)	4 (16)	13 (16)	1.0
Hospital-acquired type	9 (9)	2 (8)	7 (9)	1.0
Solid tumor, no. (%)	69 (66)	14 (56)	55 (70)	0.211
Breast	34 (33)	5 (20)	29 (37)	0.146
Gastrointestinal tract	14 (13)	4 (16)	10 (13)	0.738
Lung	7 (7)	0	7 (9)	0.191
Hepatobiliary tract	6 (6)	2 (8)	4 (5)	0.628
Ovary	3 (3)	0	3 (4)	1.0
Others	5 (5)	3 (12)	2 (3)	0.088
Stage IV	34	10	24	0.712
Hematological malignancy, no. (%)	35 (34)	11 (44)	24 (30)
Leukemia	11 (11)	5 (20)	6 (8)	0.211
History of Chemotherapy
none	3	1	2
oral chemotherapy	5	3	2
Intravenous chemotherapy	96	21	75
Latency > 2 months	7	3	4
< 2months, days	12.5 (10-15)	11 (7.7-13.0)	12.5 (10-15)	0.043^∗

<0.05, ^∗∗p<0.01 ^∗∗∗p<0.001: significant change from baseline values.
ED: emergency department.