Research Article
Advancing Parental Age and Risk of Solid Tumors in Children: A Case-Control Study in Peru
Table 1
Characteristics of children diagnosed with cancer and controls (2012-2015).
| Characteristic | Cases | | Controls | | P value |
| | N | | N | | |
| Age, years | | | | | 0.119 |
| | <1 | 16 | 5.2 | 42 | 6.8 | |
| | 01-04 | 83 | 26.8 | 145 | 23.4 | |
| | 05-09 | 76 | 24.5 | 167 | 26.9 | |
| | 10-14 | 87 | 28.1 | 171 | 27.6 | |
| | 15-18 | 48 | 15.5 | 95 | 15.3 | |
| Sex | | | | | 0.963 |
| | Male | 175 | 56.5 | 349 | 56.3 | |
| | Female | 135 | 43.6 | 271 | 43.7 | |
| Origin | | | | | 0.349 |
| | Coast | 233 | 75.2 | 485 | 78.2 | |
| | Andean | 59 | 19.0 | 95 | 15.3 | |
| | Forest | 18 | 5.8 | 40 | 6.5 | |
| Maternal age at birth, years | | | | | 0.239 |
| | <20 | 17 | 5.5 | 36 | 5.8 | |
| | 20-24 | 88 | 28.4 | 138 | 22.3 | |
| | 25-29 | 72 | 23.2 | 194 | 31.3 | |
| | 30-34 | 81 | 26.1 | 135 | 21.8 | |
| | >35 | 52 | 16.8 | 117 | 18.9 | |
| | Mean (SD) | 28.92 (6.30) | | 28.47 (6.16) | | |
| | Missing | 1 | | 8 | | |
| Paternal age at birth, years | | 0.520 |
| | <20 | 4 | 1.3 | 15 | 2.8 | |
| | 20-24 | 40 | 12.9 | 67 | 12.6 | |
| | 25-29 | 85 | 27.5 | 128 | 24.1 | |
| | 30-34 | 81 | 26.2 | 122 | 23.0 | |
| | >35 | 99 | 32.0 | 199 | 37.5 | |
| | Mean (SD) | 31.74 (6.82) | | 32.37 (7.82) | | |
| | Missing | 1 | | 89 | | |
| Education level of the mother | | 0.801 |
| | Elementary school | 26 | 8.5 | 22 | 9.6 | |
| | High school | 116 | 37.8 | 90 | 39.3 | |
| | Higher education | 165 | 53.8 | 117 | 51.1 | |
| | Missing | 3 | | 391 | | |
| Education level of the father | 0.039 |
| | Elementary school | 9 | 2.9 | 14 | 6.2 | |
| | High school | 100 | 32.7 | 87 | 38.5 | |
| | Higher education | 197 | 64.4 | 125 | 55.3 | |
| | Missing | 4 | | 394 | | |
| Birth order | | 0.002 |
| | 1 | 188 | 60.8 | 354 | 57.1 | |
| | 2 | 84 | 27.2 | 175 | 28.2 | |
| | 3 | 26 | 8.4 | 63 | 10.2 | |
| | 4 | 10 | 3.2 | 15 | 2.4 | |
| | >=5 | 1 | 0.3 | 13 | 2.1 | |
| | Missing | 1 | | 0 | | |
| Twins | | | | | 0.090 |
| | Yes | 2 | 0.6 | 7 | 1.1 | |
| | No | 308 | 99.4 | 613 | 98.9 | |
| TOTAL | | 310 | 100.0 | 620 | 100.0 | |
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