Clinical and Molecular Characteristics Associated with Survival in Advanced Melanoma Treated with Checkpoint Inhibitors

Table 2

Baseline characteristics of patient demographics.

	CheckMate 037 Larkin et al. 2017		CheckMate 066 Robert et al. 2015		CheckMate 067 Wolchok et al. 2017			CheckMate 069 Hodi et al. 2016		KEYNOTE-002 Ribas et al. 2015			KEYNOTE-006 Schachter et al. 2017
Phase	III		III		III			III		II			III
No. of Patients	405		418		945			142		540			834
Arms	Nivo	ICC	Nivo	Daca	Nivo+Ipi	Nivo	Ipi	Nivo+Ipi	Ipi	Pemb 1	Pemb 2	ICC	Pemb 1	Pemb 2	Ipi
No in arm.	272	133	210	218	314	316	315	95	47	176	177	167	279	277	278
Male	176	85	121	125	NR^1	NR^1	NR^1	63	32	104	109	114	161	174	162
Female	96	48	89	83	NR^1	NR^1	NR^1	32	15	76	72	65	118	103	116
Age in years median	59	62	64	66	NR^1	NR^1	NR^1	64	67	62	60	63	61	63	62
ECOG 0	162	84	148	121	230	237	224	79	37	98	98	99	196	189	188
ECOG 1	110	48	60	84	83	79	91	14	10	80	83	80	83	88	90