Review Article
Research Priorities and Resource Allocation in the Investigation of New Drugs for Cancer in Least Developed Countries
Table 1
Number of clinical trials with patients with cancer by phase of development.
| Country | Phase 1 | Phase 1/2 | Phase 1/3 | Phase 2 | Phase 2/3 | Phase 3 | Phase 3/4 | Phase 4 | Not Stated | Total |
| Argentina | 1 | 0 | 0 | 7 | 0 | 35 | 0 | 0 | 1 | 44 | Brazil | 1 | 2 | 1 | 6 | 0 | 33 | 0 | 2 | 2 | 47 | Chile | 0 | 0 | 1 | 1 | 0 | 16 | 0 | 1 | 0 | 19 | China | 21 | 21 | 0 | 83 | 13 | 63 | 0 | 34 | 19 | 257 | Colombia | 0 | 0 | 0 | 3 | 0 | 15 | 0 | 1 | 0 | 19 | Denmark | 5 | 5 | 0 | 26 | 1 | 26 | 0 | 4 | 0 | 67 | Egypt | 0 | 0 | 0 | 2 | 1 | 10 | 1 | 2 | 0 | 16 | Estonia | 0 | 0 | 0 | 2 | 0 | 8 | 0 | 0 | 0 | 10 | Finland | 1 | 2 | 0 | 8 | 0 | 17 | 0 | 5 | 0 | 33 | France | 19 | 14 | 0 | 40 | 3 | 37 | 0 | 3 | 0 | 116 | Germany | 13 | 8 | 0 | 44 | 5 | 34 | 0 | 3 | 5 | 112 | India | 5 | 1 | 1 | 6 | 3 | 27 | 2 | 12 | 20 | 77 | Iran | 1 | 1 | 0 | 9 | 5 | 6 | 0 | 0 | 7 | 29 | Israel | 3 | 7 | 0 | 18 | 0 | 43 | 0 | 1 | 0 | 72 | Italy | 2 | 8 | 1 | 38 | 1 | 34 | 0 | 2 | 1 | 87 | Japan | 17 | 7 | 0 | 35 | 1 | 13 | 0 | 2 | 12 | 87 | Malaysia | 0 | 0 | 0 | 4 | 1 | 16 | 2 | 1 | 0 | 24 | Mexico | 1 | 1 | 1 | 5 | 0 | 38 | 0 | 2 | 0 | 48 | Netherlands | 30 | 25 | 1 | 48 | 1 | 57 | 0 | 13 | 2 | 177 | Peru | 1 | 0 | 0 | 2 | 0 | 17 | 0 | 0 | 0 | 20 | Philippines | 0 | 0 | 1 | 4 | 1 | 25 | 0 | 1 | 0 | 32 | Russia | 2 | 4 | 1 | 19 | 2 | 51 | 1 | 2 | 0 | 82 | Singapore | 8 | 15 | 0 | 19 | 1 | 24 | 0 | 1 | 1 | 69 | South Africa | 0 | 0 | 1 | 0 | 0 | 23 | 1 | 0 | 0 | 25 | South Korea | 18 | 7 | 1 | 21 | 2 | 27 | 0 | 3 | 7 | 86 | Spain | 17 | 14 | 1 | 28 | 2 | 36 | 0 | 1 | 0 | 99 | Thailand | 2 | 4 | 0 | 11 | 1 | 30 | 2 | 3 | 0 | 53 | Turkey | 0 | 1 | 1 | 2 | 0 | 33 | 1 | 0 | 0 | 38 | Ukraine | 2 | 3 | 1 | 3 | 1 | 29 | 0 | 0 | 1 | 40 | United K. | 24 | 12 | 0 | 32 | 3 | 33 | 0 | 1 | 6 | 111 | United States | 170 | 59 | 1 | 123 | 3 | 35 | 0 | 4 | 32 | 427 |
|
|