Small or Non-Small Cell Lung Cancer Based Therapy for Treatment of Large Cell Neuroendocrine Cancer of The Lung? University of Cincinnati Experience

Table 2

Showing analysis of overall mortality for 26 patients of LCNEC of the lung.

Cox-regression analysis of overall mortality (events =18/26)	Univariate analysis				Multivariable analysis
	HR	95 CI		P value	HR	95 CI		P value
		Lower	Upper			Lower	Upper
Age	0.95	0.90	0.99	0.032	0.99	0.92	1.07	0.797
Gender
Female	Reference
Male	1.19	0.47	3.03	0.720
Race
White	Reference
African American	1.50	0.59	3.81	0.394
Smoking History
Non-Smoker	Reference
Former/Current Smoker	0.81	0.29	2.28	0.688
Stage
Stages I/II	Reference
Stages III/IV	2.26	0.75	6.43	0.128
Chemotherapy Regimen
A	Reference				Reference
B	1.12	0.36	3.53	0.847	1.09	0.34	3.50	0.882
C	0.26	0.08	0.87	0.029	0.30	0.05	1.81	0.190
Univariate variables with P value <0.1 were included in the multivariable model.

A: SCLC chemotherapy, B: NSCLC chemotherapy, C: no chemotherapy (surgical), and HR: hazard ratio.