The Impact of Addition of Consolidation Chemotherapy to Standard Cisplatin-Based Chemoradiotherapy in Uterine Cervical Cancer: Matter of Distant Relapse

Table 3

Multivariate analysis for distant metastasis free survival and locorregional free survival.

	DMFS^1		LRFS^2
Characteristic	HR (95% CI)	p value	HR (95% CI)	p value
Consolidation CT
No	1	0.028	-	-
Yes	0.43 (0.21-0.91)		-
FIGO Stage
< IIB	-	-	1	0.009
> IIIA	-		3.62 (1.37-9.49)
Grade
1 and 2	-	-	1	0.009
3	-		3.36 (1.35-8.32)
Lymph node
Negative	1	0.001	-	-
Positive	2.99 (1.54-5.81)		-
Concurrent CT < 6 cycles
No	-	-	1	0.022
Yes	-		2.82 (1.16-6.81)
Radiotherapy technique
3D	1	0.196
2D	1.51 (0.81-2.80)

174 patients with complete data included in the multivariate analysis, 46 events.
² 133 patients with complete data included in the multivariate analysis, 20 events.
DMFS = distant metastasis free survival; LRFS = locorregional free survival; CT = chemotherapy.