Interfering Expression of Chimeric Transcript SEPT7P2-PSPH Promotes Cell Proliferation in Patients with Nasopharyngeal Carcinoma

Figure 3

Knocking down SEPT7P2-PSPH can promote cell proliferation and colony formation of NPC cells. (a) CCK8 assays showed that cell proliferation was significantly enhanced after the specific siRNA interfered with the expression of SEPT7P2-PSPH (n = 3; two-tailed Student’s t-tests, < 0.05, < 0.01 and < 0.001). (b) and (c) Knocking down SEPT7P2-PSPH by siRNA can promote the colony-formation ability of CNE1 and 6-10B cells (n = 3; two-tailed Student’s t-tests, < 0.01 and < 0.001). (d) Cell migration and invasion assays revealed that the abilities of migration and invasion were enhanced after interfering with specific siRNA.

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