Low GAS5 Levels as a Predictor of Poor Survival in Patients with Lower-Grade Gliomas

Figure 6

Multivariate survival analysis of GAS5 and clinical and molecular characteristics in LGG patients. Data are AUC (95% CI) or p values. ROC: receiver operating characteristic. AUC: area under the curve. (a) The nomogram to predict overall survival in LGG patients. (b) Plots depict the calibration of each model in terms of agreement between predicted and observed 3-year and 5-year outcomes. Model performance is shown by the plot, relative to the 45-degree line, which represents perfect prediction. (c) Time-dependent ROC curves indicate the prognostic accuracy of the nomogram over 3 and 5 years. We used AUCs at 3 and 5 years to assess prognostic accuracy. (d) Kaplan-Meier survival analysis was conducted for LGG patients in the high-risk-score group and the low-risk-score group from a Cox regression model, and p values were calculated using the log-rank test.

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