Dovitinib Triggers Apoptosis and Autophagic Cell Death by Targeting SHP-1/p-STAT3 Signaling in Human Breast Cancers

Figure 4

Dovitinib induced apoptosis in breast cancer cells. Human breast cancer cells were exposed to dovitinib at the indicated doses for 24 h. The cells were fixed by EtOH and stained with propidium iodide. Apoptotic cells were measured and determined by flow cytometry. Columns, mean; bars, SD (N = 3). ; . (a) MCF-7. (b) MDA-MB-231. (c) MDA-MB-468. (d) SK-BR-3.

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