Review Article
The Role of Deubiquitinases in Oncovirus and Host Interactions
Table 2
DUBs classification.
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Six classes of DUBs in the human genome are classified into two categories, cysteine proteases, and metalloproteases. Five classes are cysteine proteases: USP, ubiquitin-specific proteases; UCH, ubiquitin carboxyl-terminal hydrolases; MJD, Machado-Joseph disease protein domain proteases; OTU, ovarian-tumor proteases; MINDY, motif interacting with Ub-containing DUB family. One class is metalloproteases: JAMM, JAMM/MPN domain-associated metallopeptidases. |