The Role of Deubiquitinases in Oncovirus and Host Interactions

Table 3

Oncoviruses encoded v-DUBs.

oncovirus	v-DUB	Deubiquitination types	targets	pathways	Ref.
EBV	BPLF1	Lys48- or; Lys63-linked polyubiquitin	TRAF6, NEMO, IκBα	Inhibits TLR signaling and NF-κB pathway	[47, 48]
KSHV	ORF64	Lys48- or; Lys63-linked polyubiquitin	RIG-I	Inhibits RIG-I-mediated-IFN signaling	[49]