Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer

Figure 1

Clinical relevance of MCAK in GEO and TCGA breast cancer datasets. Here, MCAK-high was defined as MCAK mRNA level equal to or larger than median mRNA levels in each dataset. The mRNA levels of MCAK, tumor size, lymph node involvement, and Elston grade of breast cancer were analyzed in GEO (a) and TCGA (b) datasets. The mRNA levels of MCAK in different molecular subtypes of breast cancer were also examined in NKI dataset (c) and TCGA dataset (d).

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