Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer
Table 2
Clinical relevance of miR-485 and miR-181c on GSE 22220 dataset.
has-miR-485-5p
has-miR-181c
High (%)
Low
p value†
High (%)
Low
p value†
Age
<50
41 (58.6)
29
26 (37.1)
44
≧50
63 (45.0)
77
0.0632
79 (56.4)
61
0.0081
Grade
1
27 (64.3)
15
26 (61.9)
16
2
41 (50.0)
41
47 (57.3)
35
3
40 (35.5)
73
0.0137
22 (35.5)
40
0.0092
Tumor size
<2cm
38 (58.5)
27
36 (55.4)
29
>=2cm
66 (45.5)
79
0.0823
69 (47.6)
76
0.2957
Lymph node
0
59 (49.2)
61
65 (54.2)
55
1-2
21 (47.7)
23
18 (40.9)
26
>=3
24 (52.2)
22
0.9084
22 (47.8)
24
0.3036
ER status
Negative
35 (42.7)
47
33 (40.2)
49
Positive
69 (53.9)
59
0.1120
72 (56.3)
56
0.0233
Note: there are 1, 1, 1, 5, and 1 missing cases in age, tumor size, lymph node, grade, and ER status. % represents positive rate of has-miR-485-5p/has-miR-181c is equal to N /(N +×100%. † p values were based on the Pearson Chi-square test.
