A Comprehensive Evaluation of the Association between Polymorphisms in XRCC1, ERCC2, and XRCC3 and Prognosis in Hepatocellular Carcinoma: A Meta-Analysis

Table 2

Characteristics of studies included in this meta-analysis.

Study	Year	Country	Ethnicity	Number of patients	Age	HBV	SNP loci	scores of quality evaluation
Jung1 [8]	2012	Korea	Asian	708	53.3 ± 8.3	+	xrcc1 rs25487	8
Jung2 [8]	2012	Korea	Asian	314	53.3 ± 8.3	+	xrcc1 rs25487	8
Han [10]	2012	China	Asian	112	50.8±8.5	mixed	xrcc1 rs25487, xrcc3 rs861539	7
Yue [11]	2013	China	Asian	231	50.9±9.6	mixed	xrcc1 rs25487, xrcc1 rs1799782, ercc2 rs13181, ercc2 rs1799793	7
Wu [12]	2014	China	Asian	218	52.2 ± 8.5	+	xrcc1 rs25487, xrcc1 rs1799782, ercc2 rs13181, ercc2 rs1799793	6
Wang [13]	2016	China	Asian	308	53( 25–80)	Mixed	xrcc1 rs25487,ercc2 rs13181	7
Yu [14]	2016	China	Asian	485	⩽60,418; >60,67	+	xrcc1 rs25487	7
Santonocito [15]	2017	Italy	Caucasian	89	66.3±10.5	mixed	xrcc1 rs25487	6
Guan [9]	2017	China	Asian	172	50.4±4.8	Not reported	xrcc1 rs1799782, ercc2 rs1799793	6
Avadanei [16]	2018	romania	Caucasian	50	⩽65,28; >65,22	mixed	xrcc3 rs861539	5