Noninvasive Identification of Immune-Related Biomarkers in Hepatocellular Carcinoma

Table 4

The enriched pathway of top 2 modules.

Module	Term	value	FDR	Genes
Module 1	Immune response	0.02	22.28	TNFSF10, JUN, CCR1
	Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	0.02	24.07	TNFSF10, CYCS
	Cytokine-cytokine receptor interaction	0.01	14.95	TNFSF10, CCR1, IFNG, VEGFA
	Positive regulation of epithelial cell migration	0.02	21.94	JUN, IFNG
	HIF-1 signaling pathway	0.02	22.98	IFNG, VEGFA, TLR4
Module 2	Cellular response to corticotropin-releasing hormone stimulus	<0.001	1.74	NR4A2, NR4A1
	Intracellular receptor signaling pathway	<0.001	6.26	NR4A2, NR4A1
	Steroid hormone-mediated signaling pathway	0.01	23.88	NR4A2, NR4A1
	MAPK signaling pathway	<0.001	0.90	DUSP1, NR4A1, HSPA1A
	Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	0.02	22.82	NR4A1, HSPA1A