RAD51 and XRCC3 Polymorphisms Are Associated with Increased Risk of Prostate Cancer

Table 3

Distribution of genotypes and allele frequency of studied SNPs in RAD51 and XRCC3 in prostate cancer patients and control group.

Gene	rs	Genotype/allele	Control group (n=205)	Prostate cancer patients (n=99)
RAD51	rs2619679	TT	48	30
		TA	101	51
		AA	56	18
		χ^2 = 3.59, p = 0.17
		T	197	111
		A	213	87
		χ^2 = 3.43, p = 0.06
	rs2928140	GG	95	43
		GC	63	36
		CC	47	20
		χ^2 = 1.00, p = 0.61
		G	253	122
		C	157	76
		χ^2 = 0, p = 1.00
	rs5030789	AA	29	7
		AG	106	45
		GG	70	47
		χ^2 = 6.43, p = 0.04
		A	164	59
		G	246	139
		χ^2 = 5.98, p = 0.01
XRCC3	rs1799796	AA	77	28
		AG	92	45
		GG	36	26
		χ^2 = 4.15, p = 0.13
		A	246	101
		G	164	97
		χ^2 = 4.40, p = 0.04