Comparative Efficacy and Tolerability of Neoadjuvant Immunotherapy Regimens for Patients with HER2-Positive Breast Cancer: A Network Meta-Analysis

Figure 3

Pooled estimates for all possible treatment effects for each outcome (treatments were ordered by ranking). Effect estimates reflect comparison of the treatment in the row heading being compared to the column heading. Effect estimates of all outcomes are expressed as odds ratios (ORs) with 95% credible intervals. ORs with Bayesian p value less than 0.05 are in green. C indicates chemotherapy; CL, chemotherapy plus lapatinib; CP, chemotherapy plus pertuzumab; CT, chemotherapy plus trastuzumab; CTL, chemotherapy plus trastuzumab plus lapatinib; CTP, chemotherapy plus trastuzumab plus pertuzumab; MP, trastuzumab emtansine plus pertuzumab; TP, trastuzumab plus pertuzumab.

(a) Pathologically complete response

(b) Serious adverse events

(c) Breast-conserving surgery rate