The Pancreatic Cancer-Initiating Cell Marker CD44v6 Affects Transcription, Translation, and Signaling: Consequences for Exosome Composition and Delivery

Figure 4

Assignment of CD44- and CD44v6-associated molecules to traffic engagement. Coimmunoprecipitating molecules in cells and TEX were grouped according to proteins engaged in vesicle biogenesis and transport (Panther/Reactome): CD44-associated in cells (dark red), TEX (red), cells, and TEX (red, dark red framed) and CD44v6-associated in cells (dark green), TEX (green), cells, and TEX (green, dark green framed). Full names of synonyms: Table S6. With the exception of vesicle exocytosis, traffic-associated molecules are more frequently associated with CD44v6 than CD44 in cells and TEX.