The Significant Influence of the Neuroendocrine Component on the Survival of Patients with Gastric Carcinoma Characterized by Coexisting Exocrine and Neuroendocrine Components

Figure 3

Overall survival of the patients regrouped according to the proportion of the NE component. (a) All the cases were categorized into four groups: GAC without a NE component (n=190), GAC with NED 0<NE<30% (n=32), MANEC 30%≤NE≤70% (n=29), and NEC 70%<NE<100% (n=34); there was no significant difference in OS rates among these four groups (p=0.126). We adopted 70% (b) and 90% (c) of the NE component as cut-off proportions, respectively; GAC patients with NE components >70% and >90% had significantly worse survival than GAC ones without a NE component (p=0.031 and p=0.019, respectively). (d) We adopted 70% of the NE component as the cut-off proportions to compare the survival between two groups in GAC patients with a NE component, and there was no significant difference between the two groups (p=0.190).

(a)

(b)

(c)

(d)